What if fungi could help clean our city? This project introduces fungi-based design as a sustainable and regenerative strategy for addressing Cincinnati’s urban environmental challenges in improving public health, reducing pollution, and enhancing sustainability. Drawing on the ecological power of fungi, it explores the use of mycofiltration to treat stormwater, mycoremediation to decontaminate polluted soils, and mycelium-based materials as alternatives in construction and waste reduction. Through a combination of city-scale analysis and targeted site selection, the project identifies areas of high ecological stress such as brownfields, heat islands, and toxic runoff zones with proposes modular, fungi-integrated interventions. These landscape strategies are designed to be adaptive, scalable, and ecologically rooted, aiming to restore environmental function while enhancing community well-being. Ultimately, the project reimagines fungi not just as organisms, but as collaborative agents in designing healthier, cleaner, and more sustainable urban futures.